Quality Management and Animal Welfare as Culture of Care for Animal Experiments under Biosafety Level-3, taking COVID-19 as a Practical Example
Since the start of the COVID‐19 pandemic, a tremendous amount of work has been done by scientists to understand the pathogenesis of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Several animal models have been reported to be useful for the development and testing of vaccines, ant...
Authors: | ; ; ; ; ; |
---|---|
Format: | Electronic Article |
Language: | English |
Check availability: | HBZ Gateway |
Journals Online & Print: | |
Fernleihe: | Fernleihe für die Fachinformationsdienste |
Published: |
Brill
2024
|
In: |
Journal of applied animal ethics research
Year: 2024, Volume: 6, Issue: 1, Pages: 26-52 |
Further subjects: | B
3S
B animal husbandry B Severe acute respiratory syndrome-related coronavirus 2 B data management B inactivation B culture of care B BSL B biosafety level B Housing B 3R |
Online Access: |
Volltext (lizenzpflichtig) Volltext (lizenzpflichtig) |
MARC
LEADER | 00000caa a22000002 4500 | ||
---|---|---|---|
001 | 1895372747 | ||
003 | DE-627 | ||
005 | 20240714034554.0 | ||
007 | cr uuu---uuuuu | ||
008 | 240713s2024 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1163/25889567-bja10047 |2 doi | |
035 | |a (DE-627)1895372747 | ||
035 | |a (DE-599)KXP1895372747 | ||
040 | |a DE-627 |b ger |c DE-627 |e rda | ||
041 | |a eng | ||
084 | |a 0 |a 1 |2 ssgn | ||
100 | 1 | |a Richter, Armina |e VerfasserIn |4 aut | |
245 | 1 | 0 | |a Quality Management and Animal Welfare as Culture of Care for Animal Experiments under Biosafety Level-3, taking COVID-19 as a Practical Example |
264 | 1 | |c 2024 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a Computermedien |b c |2 rdamedia | ||
338 | |a Online-Ressource |b cr |2 rdacarrier | ||
520 | |a Since the start of the COVID‐19 pandemic, a tremendous amount of work has been done by scientists to understand the pathogenesis of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Several animal models have been reported to be useful for the development and testing of vaccines, antivirals, or therapeutics. These in vivo experiments have to be performed at high containment biosafety level (BSL)-3. Thus, an appropriate biosafety, facility and data management as well as high standard of animal welfare, thorough study design, and staff training combined with an overall research transparency and open communication need to be implemented to achieve high quality reproducible research. Such an approach combined with the well-known 3R principle (Replacement, Reduction, and Refinement) and the 3S principle (Good Science, Good Sense, and Good Sensibilities) can contribute to culture of care in scientific research. The perspective reviews the key points of optimized biosafety, data, quality and animal welfare management in high risk biosafety-settings to conduct animal experiments with infectious pathogens in the context of a culture of care. | ||
601 | |a COVID-19 | ||
650 | 4 | |a SARS-CoV-2 | |
650 | 4 | |a inactivation | |
650 | 4 | |a Housing | |
650 | 4 | |a data management | |
650 | 4 | |a culture of care | |
650 | 4 | |a BSL | |
650 | 4 | |a biosafety level | |
650 | 4 | |a animal husbandry | |
650 | 4 | |a 3S | |
650 | 4 | |a 3R | |
700 | 1 | |a Wirz, Katrin |e VerfasserIn |0 (orcid)0009-0002-1840-0363 |4 aut | |
700 | 1 | |a Pilchová, Veronika |e VerfasserIn |4 aut | |
700 | 1 | |e VerfasserIn |0 (DE-588)124390005 |0 (DE-627)363314326 |0 (DE-576)294150137 |4 aut |a Schulz, Claudia |d 1968- | |
700 | 1 | |a Volz, Asisa |e VerfasserIn |4 aut | |
700 | 1 | |a Köckritz-Blickwede, Maren von |e VerfasserIn |0 (orcid)0000-0001-7712-9767 |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of applied animal ethics research |d Leiden : Brill, 2019 |g 6(2024), 1, Seite 26-52 |h Online-Ressource |w (DE-627)168461418X |w (DE-600)3002529-1 |x 2588-9567 |7 nnns |
773 | 1 | 8 | |g volume:6 |g year:2024 |g number:1 |g pages:26-52 |
856 | 4 | 0 | |u https://doi.org/10.1163/25889567-bja10047 |x Resolving-System |z lizenzpflichtig |3 Volltext |
856 | 4 | 0 | |u https://brill.com/abstract/journals/jaae/6/1/article-p26_3.xml |x Verlag |z lizenzpflichtig |3 Volltext |
912 | |a NOMM | ||
935 | |a mteo | ||
951 | |a AR | ||
ELC | |a 1 | ||
LOK | |0 000 xxxxxcx a22 zn 4500 | ||
LOK | |0 001 4550740280 | ||
LOK | |0 003 DE-627 | ||
LOK | |0 004 1895372747 | ||
LOK | |0 005 20240713055505 | ||
LOK | |0 008 240713||||||||||||||||ger||||||| | ||
LOK | |0 035 |a (DE-Tue135)IxTheo#2024-07-12#194E6DE9AD682011C3AB62CAF6447743A54D2161 | ||
LOK | |0 040 |a DE-Tue135 |c DE-627 |d DE-Tue135 | ||
LOK | |0 092 |o n | ||
LOK | |0 852 |a DE-Tue135 | ||
LOK | |0 852 1 |9 00 | ||
LOK | |0 935 |a ixzs |a zota | ||
ORI | |a SA-MARC-ixtheoa001.raw | ||
REL | |a 1 | ||
STA | 0 | 0 | |a Severe acute respiratory syndrome-related coronavirus 2 |
STB | 0 | 0 | |a SARS-CoV-2 (virus) |
STC | 0 | 0 | |a SARS-CoV-2 |
STD | 0 | 0 | |a SARS-CoV-2,SARS-CoV-2 |
STF | 0 | 0 | |a 嚴重急性呼吸綜合症冠狀病毒2型 |
STG | 0 | 0 | |a Coronavírus da síndrome respiratória aguda grave 2 |
STH | 0 | 0 | |a SARS-CoV-2 |
STI | 0 | 0 | |a SARS-CoV-2 |
SUB | |a REL | ||
SYE | 0 | 0 | |a Schweres akutes Atemwegssyndrom Coronavirus 2,Severe acute respiratory syndrome coronavirus 2,2019-nCoV,2019-novel Corona virus,Wuhan-Coronavirus |