The Role of Patient Religiosity in the Evaluation and Treatment Outcomes for Chronic HCV Infection
To determine the influence of patient religiosity on the outcome of treatment of hepatitis C infection, a prospective, blinded, cohort study was performed on hepatitis C-infected patients categorized as higher religiosity' and lower religiosity' based on responses to a religiosity questi...
| Published in: | Journal of religion and health |
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| Subtitles: | The Role of Patient Religiosity in the Evaluation and Treatment Outcomes for Chronic Hepatitis C Virus Infection |
| Authors: | ; ; ; ; |
| Format: | Electronic Article |
| Language: | English |
| Check availability: | HBZ Gateway |
| Journals Online & Print: | Drawer...
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| Fernleihe: | Fernleihe für die Fachinformationsdienste |
| Published: |
Springer Science + Business Media B. V.
[2013]
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| In: |
Journal of religion and health
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| Further subjects: | B
Religion
B HCV B Hepatitis C virus B Religiosity B SF-36 |
| Online Access: |
Volltext (Resolving-System) |
| Summary: | To determine the influence of patient religiosity on the outcome of treatment of hepatitis C infection, a prospective, blinded, cohort study was performed on hepatitis C-infected patients categorized as higher religiosity' and lower religiosity' based on responses to a religiosity questionnaire. Comparisons were made between high and low religiosity patients on demographics, pre-treatment laboratory values, and response to treatment. Eighty-seven patients with complete questionnaires were placed in either higher (38) or lower (49) religiosity cohort. The patients (60% female) were ethnically diverse: African-American 39%; Hispanic 31%; white 29%. African-American race (P = 0.001) and female gender (P = 0.026) were associated with higher religiosity. The frequency of being offered treatment, accepting treatment, and completing treatment was similar in both religiosity cohorts (P = 0.234, 0.809, 0.367). Fifty-six patients completed the 24- or 48-week treatment with peginterferon and ribavirin. Depression was more frequent in the low religiosity group (38.2% vs. 4.6%, P = 0.005). Sustained viral response rate at 3-6-month post-therapy was similar in the higher (50%) and lower (57.6%) religiosity cohorts (P = 0.580; n = 55). Logistic regression modeling revealed that males having higher religiosity gave greater odds of SVR than those with lower religiosity (OR 21.3; 95% CI 1.1-403.9). The level of religiosity did not affect the decision to begin treatment for chronic HCV infection and was not associated with a better treatment outcome. A higher level of religiosity was associated with less depression among patients. |
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| ISSN: | 1573-6571 |
| Contains: | Enthalten in: Journal of religion and health
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| Persistent identifiers: | DOI: 10.1007/s10943-011-9455-y |